v5.4.2 (Database Updated 02/20/2018)

Database updated on 02/20/2018 with 1003 changes
Gene annotation version 6.19
FlyBase ontology version 09/06/2017

Welcome to REDfly
Regulatory Element Database for Drosophila v5.4.2
REDfly version 5.4.2 released!
REDfly now has predicted CRM data.

Note: Inferred CRM calculation is not up to date.

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Thank you for visiting REDfly! We are hard at work bringing you new features and a better user experience. We want to hear where you want to see us go!
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REDfly is a curated collection of known Drosophila transcriptional cis-regulatory modules (CRMs) and transcription factor binding sites (TFBSs). Despite more than 20 years of experimental determination of these elements, the data have never been collected into a single searchable database. REDfly seeks to include all experimentally verified fly regulatory elements along with their DNA sequence, their associated genes, and the expression patterns they direct. Expression patterns are annotated using a defined anatomy ontology to enable high interoperability with FlyBase, FlyExpress, the BDGP in situ hybridization database, and other model organism resources.

If you know of experimentally verified cis-regulatory elements that are not included in the REDfly database, or have corrections to the archived data, please contact us.

REDfly has 16503 CRMs (6212 from in vivo reporter genes, 10276 from cell-culture assays, and 15 from other evidence), associated with 722 genes, and 2198 TFBSs bound by 175 transcription factors acting on 242 target genes. These data are based on 767 curated publications.

The regulatory data curated by REDfly are the result of the hard work of members of the Drosophila community. When using specific CRM and TFBS data, please make sure to cite the original discoverers.

Funded in part by the NSF and the NIGMS

Copyright © University at Buffalo—State University of New York. REDfly is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International license. The copyrights of all curated content belong to their respective owners.