Database updated on 27-Sep-2017 with 3 changes

REDfly version 5.3.1 released!
REDfly now has the latest FlyBase anatomy ontology.
Regulatory Element Database for Drosophila v5.3.1


Welcome to REDfly

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REDfly now supports search by locus feature

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REDfly is a curated collection of known Drosophila transcriptional cis-regulatory modules (CRMs) and transcription factor binding sites (TFBSs). Despite more than 20 years of experimental determination of these elements, the data have never been collected into a single searchable database. REDfly seeks to include all experimentally verified fly regulatory elements along with their DNA sequence, their associated genes, and the expression patterns they direct. Expression patterns are annotated using a defined anatomy ontology to enable high interoperability with FlyBase, FlyExpress, the BDGP in situ hybridization database, and other model organism resources.

If you know of experimentally verified cis-regulatory elements that are not included in the REDfly database, or have corrections to the archived data, please contact us.

REDfly has 16180 CRMs (5892 from in vivo reporter genes, 10274 from cell-culture assays, and 14 from other evidence), associated with 630 genes, and 2073 TFBSs bound by 159 transcription factors acting on 216 target genes. These data are based on 696 curated publications.

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The regulatory data curated by REDfly are the result of the hard work of members of the Drosophila community. When using specific CRM and TFBS data, please make sure to cite the original discoverers.


Funded in part by the NSF and the NIGMS