Last update on 03-Jun-2015 with 78 changes

REDfly version 4.0 released!
REDfly updated to include R6 coordinates.
Regulatory Element Database for Drosophila v4.0


Welcome to REDfly

REDfly updated to include R6 coordinates.

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REDfly is a curated collection of known Drosophila transcriptional cis-regulatory modules (CRMs) and transcription factor binding sites (TFBSs). Despite more than 20 years of experimental determination of these elements, the data have never been collected into a single searchable database. REDfly seeks to include all experimentally verified fly regulatory elements along with their DNA sequence, their associated genes, and the expression patterns they direct. Expression patterns are annotated using a defined anatomy ontology to enable high interoperability with FlyBase, FlyExpress, the BDGP in situ hybridization database, and other model organism resources.

If you know of experimentally verified cis-regulatory elements that are not included in the REDfly database, or have corrections to the archived data, please contact us.

REDfly has 5577 CRMs associated with 552 genes, and 2058 TFBSs bound by 158 transcription factors acting on 212 target genes. These data are based on 680 curated publications.

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The regulatory data curated by REDfly are the result of the hard work of members of the Drosophila community. When using specific CRM and TFBS data, please make sure to cite the original discoverers.


Funded in part by the National Science Foundation